Martin Gruebele
Director of the Center for
Biophysics and Computational Biology;
William H. & Janet Lycan Professor of Chemistry;
Professor of Physics and Biophysics
Professor Gruebele received his B.S. degree in 1984, and his Ph.D. in 1988 from the University of California at Berkeley. After working as a postdoctoral fellow at the California Institute of Technology, he joined the faculty of the University of Illinois in 1992. Dr. Gruebele is also a faculty member of the Beckman Institute.
Research
The Gruebele Group is engaged in experiments and computational modeling to study a broad range of fundamental problems in chemical and biological physics. A common theme in these experiments is the implementation of state-of-the-art laser techniques to interrogate and manipulate complex molecular systems, coupled with quantum or classical simulations. The results of these efforts are contributing to a deeper understanding of the way that proteins fold into functional 3-dimensional molecules, the details of how chemical bonds are broken by vibrational motion and how this can be controlled, and the switching of energy flow in large molecular structures on surfaces.Publications
E. L. Sibert III and M. Gruebele, "Molecular vibrational dynamics and dilution factors in an anharmonic state space," J. Chem. Phys. 124, 024317 (2006).
H. Ma, D. Proctor, P. Bevilacqua and M. Gruebele, "Exploring the RNA hairpin energy landscape by temperature tuning," J. Am. Chem. Soc. 128, 1523-1530 (2006).
D. Leitner, M. Havenith and M. Gruebele, "Biomolecule large amplitude motion and solvation dynamics: Modeling and probes from THz to X-rays," Int. Rev. Phys. Chem. , 25, 553-582 (2006).
C. Dumont, Y. Matsumura, S. J. Kim, J. S. Li, E. Kondrashkina, H. Kihara and M. Gruebele, "Solvent-tuning the collapse and secondary structure formation of λ6-85," Prot. Sci. 15, 2596-2604 (2006).
P. M. Chowdary, B. Strickler, S. Lee and M. Gruebele, "The A-X SEP spectrum of jet-cooled thiophosgene," Chem. Phys. Lett. 434, 182-187 (2007).
E. S. Carmichael, J. B. Ballard, J. W. Lyding and M. Gruebele, "Frequency-modulated single molecule absorption spectroscopy," J. Phys. Chem. 111, 3314-3321 (2007).
P. D. Chowdary, T. J. Martínez and M. Gruebele, "The vibrationally adiabatic torsional potential energy surface of trans-stilbene," Chem. Phys. Lett. 440, 7-11 (2007).
F. Liu and M. Gruebele, "Tuning λ6-85 towards downhill folding near the unfolding transition midpoint," J. Mol. Biol. 370, 574-584 (2007).
D. Weidinger and M. Gruebele, "Quantum computation with energy-multiplexed molecular vibrations," Mol. Phys. 10, 1999-2008 (2007).
M. Gruebele and P. G. Wolynes, "Quantizing Ulam’s control conjecture," Phys. Rev. Lett., 99, 060201 (2007).
Awards
- Friedrich Wilhelm Bessel Prize, von Humboldt Society
- Coblentz Award, Coblentz Society
- Dreyfus New Faculty Award
- NSF National Young Investigator Award
- Packard Fellowship
- Cottrell Scholarship
- Fellow, Center for Advanced Study, UIUC
- A. P. Sloan Fellow
- Camille and Henry Dreyfus Fellow
- University Scholar, UIUC
- Fellow of the American Physical Society
- Associate, Center for Advanced Study
- NSF Creativity Extension Award
- Baker Symposium Lecturer
